Taken together, these results strongly imply that the constituents of a transgene array have minimal impact on the expression of one another.
We checked whether these elements have an impact on the expression of the adjacent gene.
In contrast, leptin had no impact on the expression of PPARα in liver, skeletal muscle or adipose tissue.
To identify whether deglycosylation has an impact on the expression of Dmp1, we examined the Dmp1 mRNA expression levels by using qPCR in different brain regions.
For all of the topographies, there was limited impact on the expression of CCL-3 and CCL-2, whereas, there was a mild elevation in IL-6 expression.
Such a dynamic impact on the expression and function of hGRα might possibly explain why GC are beneficial only when administered early in sepsis [28].
MRTFA also regulates the expression of EMT-associated transcription factors including Snail, Slug, and Twist [105] and therefore may have an impact on the expression of the epithelial gene E-cadherin.
All steps of an experimental protocol have to be investigated with respect to their impact on the expression profile because even routine procedures, such as the concentration of bacteria by centrifugation, can change the expression profile.
In the present study, we administered polyphosphazene (PCEP), CpG oligodeoxynucleotides (CpG), emulsigen or saline via an intradermal injection into pigs and assessed the impact on the expression of reported 'adjuvant response genes' over time.
The increased level of non-avoidance of faeces displayed by cows housed in cubicles indicated that housing design might have had a negative impact on the expression of eliminate-avoidance behaviour.
High content analysis showed that 4e and 4m induced a dose-dependent increase of dimethylated Lys4 of histone H3 and had no impact on the expression of LSD1 in MGC-803 cells.
