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Loss of our biodiversity can have a major adverse impact on discovery of new remedies for cancer.
The impact on discovery of biological differences (for example impact of smoking on gene expression profile [ 12]), was assessed by power calculations.
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Partnerships between the Nicholas School and foundations can have powerful impacts on discovery, innovation and leadership in the environmental realm, providing value for society as a whole and helping both organizations achieve our goals.
Collaborations between the Nicholas School and private sector partners can have powerful impacts on discovery, innovation and leadership in the environmental realm, providing value for society as a whole and for your business's bottom line.
Combinatorial chemistry (combichem) has had a significant impact on the discovery of new antibiotics.
Recent decreases in government funding and reformed educational policies could, however, seriously impact on drug discovery initiatives worldwide.
Because natural products have been a major source of therapeutic molecules, methods that rationally activate these silent clusters would have a profound impact on drug discovery.
Protein crystallography has traditionally been regarded as a resource-intensive, time-consuming technique that, with some notable exceptions, has not made a significant impact on drug discovery.
Examples of both types of application are discussed and it is suggested that both approaches will have a substantial impact on drug discovery in the future.
Ligand-biased signaling is starting to have significant impact on drug discovery programs in the pharmaceutical industry and has reinvigorated our understanding of pharmacological efficacy.
The clinical success of cisplatin and its derivatives has had an enormous impact on the discovery of novel metal-based drugs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com