Sentence examples for impact of this mutation from inspiring English sources

But we cannot grasp the full psychological impact of this "mutation in human nature" in purely secular terms.

Using computations and experiments, we examine the impact of this mutation on the stability and conformational dynamics of the mini-intein splicing domain.

A lack of power resulting from our difficulty to recruit enough T73T women precludes any definitive conclusion regarding the impact of this mutation on caloric compensation.

Despite the functionality of the -151C/T GHSR mutation we did not find a significant impact of this mutation in the general population of adult Danes.

This favors a specific functional consequence such as a dominant negative effect or a change or gain of function as opposed to a generic loss of function and the ultimate impact of this mutation is oncogenic.

The differences in the impact of this mutation on the ability of mice to clear Mp and M. pulmonis suggest that there may be microbial strain-specific aspects of the host response to this family of organisms.

Since swarming of P. aeruginosa is dependent on rhamnolipid production [8], we evaluated the impact of the mutation on this biosynthesis.

The impact of the mutation in this patient is still questioning as JAK2V617F in thrombotic syndromes is frequent in splanchnic vein thrombosis, but extremely rare in unprovoked thrombosis.

Although the actual impact of the mutation on this ESS element remains to be determined, it is tantalizing to speculate that binding of SR proteins to the novel ESE motif created by the nucleotide transition may pose potential steric hindrance to the binding of hnRNP proteins to ESS, thereby compromising its repression on exonic splicing.

The elements of alternating rows contain mutation scores based on synonymous and non-synonymous mutations, which we define M ij _* (the wild card, * = non-synonymous/synonymous mutations (NSY/SY)) for gene i in sample j as the number of mutated bases, weighted by the functional impact score of this mutation, divided by the total number of bases that have sufficient read depth.

These experiments demonstrated no impact of this escape mutation in the epitope on interactions with ILT4 on monocytes (Figure 2).