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The presented data confirms the deleterious impact of the altered C-terminus resulting from the branch-site mutation.
In the study presented here, the specific impact of the altered p53 status on extrinsic and intrinsic apoptosis induction was studied in detail.
Therefore, variation in the molecular context of developing skeletal rudiments in different parts of the developing fore and hind limbs may influence the impact of the altered mechanical environment resulting from absence of muscles.
Physicochemical, macromolecular, and biological pathways contribute to assessing the impact of the altered activities of ENPs on the surrounding environmental matrices.
We use computational modelling to predict the impact of the altered organization of RyR clusters and CRUs on Ca2+ release, comparing predictions to observations of spark properties.
Finally, to evaluate the prognostic impact of the altered TSS usage, immunohistochemistry was used to show deregulation of the total protein levels of both TCF12 and OSBPL1A, corresponding to the mRNA levels observed.
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Next, we address the selective impacts of the altered interactions with other trophic levels predicted to occur with density changes.
The results are discussed in terms of the origins and impact of these altered RNAs, the role of the Pol III complex as a type of boundary element, and how compromising association of particular chromatin binding complexes can have unforeseen global impacts on both the transcriptome and the proteome.
The impact of this altered immune response on secondary infections is poorly reported in children affected by septic shock.
However, the impact of this altered metabolism on pregnant women's or children's health is not well established.
The impact of the ectopically altered TM8 expression on the reproductive structures suggests that this gene plays some role in the development of the tomato flower.
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