Exact(7)
Herein, we propose an approach combining several classification and chemography methods to be able to predict chemical liabilities and to interpret obtained results in the context of impact of structural changes of compounds on their pharmacological profile.
This work concerns an approach that combines several classification and chemography methods for in silico assessment of chemical liabilities and for the interpretation of obtained results in the context of impact of structural changes of compounds on their pharmacological profile.
Herein, we propose an approach combining several classification and chemography [3] methods to assess chemical liabilities in silico and to interpret obtained results in the context of impact of structural changes of compounds on their pharmacological profile.
We conducted uncertainty and sensitivity analyses of the key parameters in the model, examined the size of the epidemiologic synergy as a function of susceptibility and infectivity enhancements, and discussed the impact of structural changes in the model such as explicit incorporation of other sexually transmitted infections in the model.
The IR and ESR measurements may be supplemented by microhardness testing (MH) that verifies the impact of structural changes to local mechanical properties.
In the DHIS, there was no discrimination between utilization of private and public health care, implying that it was not possible to assess the impact of structural changes in the health care system in the studied period.
Similar(53)
The use of REIMs, such as CREIM, to study the impacts of structural changes in a regional economy and their impacts on emissions inventories is a reasonable choice, since interindustry impacts need to be traced and the temporal staging of effects needs to be broken out.
The committee's chairman, John Whittingdale, the Conservative MP for Maldon and East Chelmsford, said local media performed a vital function "yet local media face unprecedented challenges as a result of structural changes and the impact of a global recession.
Regardless of structural changes, Met oxidation can have a large impact on protein functionality, including interactions with other proteins.
His suspicion of structural changes goes further, however.
Collier withdraws to mull over these proposals of structural changes.
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