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To analyze the impact of breadth of T cell immunity to Gag (i.e. other than KP9-specific responses), we performed intracellular cytokine staining assays for T cell activation using 5 pools of 25 overlapping 15mers peptides spanning the entire SIV Gag protein as previously described [27].
To assess any impact of breadth of participation, two indices were constructed by summing the items endorsed.
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Assuming distributions do not change dramatically over longer time periods, excluding these serotypes from a vaccine would have little impact on breadth of coverage.
While this represents perhaps three percent of the total enrollment in American colleges and universities, the impact on breadth, access and choice would be catastrophic.
By summarizing their extensive contributions, a perspective is given as to the impact and breadth of their observations and recommendations on quality improvement for specific operations in various specialties under various conditions.
Ken Cunningham, general secretary of SLS said: "There is still unease that it is not the choice of the SQA to have a compulsory question and we will be keeping a close eye on the impact of this on the breadth of learning of literature in Scottish schools".
Nonetheless, the potential impact of diet on scratch breadth will need to be accounted for where appropriate.
Nick Clegg has disclosed that the business department is undertaking a review of the breadth and impact of zero-hours contracts.
The breadth and impact of these privately financed groups have made them, and the mystery of their backers, a campaign issue in their own right.
Glover had a team of only five people, which she herself said limited the breadth and impact of her work.
The objective of this paper is to evaluate the impact of changing the number and breadth of land use classes on a model's calibration and predictions.
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