Sentence examples for impact lifespan from inspiring English sources

This conclusion is supported by the finding that dwarfism and CR may impact lifespan through independent mechanisms [19], and the finding that GH deficiency and CR display minimal overlap at the gene expression level [20].

However, induction of C. elegans DR by limiting the amount of bacteria on plates suggests a lifespan-extending mechanism that is DAF-16-dependent [34], indicating that distinct food deprivation regimens may signal through different pathways to impact lifespan.

We also assessed aging in these animals and found a significant reduction in lifespan under nutrient-rich conditions (Figure S5), although reduced AMPK function did not significantly impact lifespan for younger cohorts used for starvation studies.

In addition, there is focal respiratory chain deficiency in a variety of organs in aged humans and the combined cell loss in all tissues may be substantial and impact lifespan.

In cockroaches, it has been found that this self-regulation of diet can significantly impact lifespan and reproductive fitness [ 65], indicating the adaptive significance of this ability to modulate feeding behavior.

Finally we used a biochemical approach to identify putative O-GlcNAc target proteins, and found that the majority of these proteins are regulated by insulin signaling, and a significant percentage functionally impact lifespan.

To the extent that a proximal factor impacting lifespan is expected to vary in abundance in proportion to longevity, however, Pearson log-linear correlations have the merit of preserving that information.

Lachnospiraceae is known to have an impact on lifespan, healthy phenotypes and the immune responses (Maldonado-Contreras et al. 2011).

Six other sweeteners four artificial, two natural had no impact on lifespan, the team reports online today in PLOS ONE.

Such variations are known to create damaging thermal stresses within the stack and thus, impact overall lifespan.

Therefore, the use of pre-depleted medium does not alter the mechanisms by which nutrient signaling pathways impact chronological lifespan.