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The phrase "impact is significant" is correct and usable in written English.
You can use it any time you want to emphasize the importance or far-reaching effects of something. For example: "The introduction of this new technology will have a significant impact on the efficiency of our organization."
Exact(30)
The impact is significant.
"The economic impact is significant".
The impact is significant and real.
In that sense the impact is significant.
The impact is significant and cannot be emphasised enough.
"Where the impact is significant is real estate," Guselnikov continued.
Similar(30)
But Upham's impact was significant.
"You can't recreate the millennium," Mr. Pittelli said, adding that the loss of advertising impact was significant.
A survey of more than 230 of the 2,100 groups across the UK found the social impact was significant.
These include a name that may not be as well known but whose cultural impact was significant: Moms Mabley.
The efforts of the #NoAmazon coalition, as the group called itself, have largely gone unreported until now but their impact was significant.
More suggestions(18)
impact is vital
consequence is significant
impact is huge
effect is significant
impact is tremendous
incidence is significant
impact is substantial
impact is major
impact is notable
impact is noteworthy
impact is large
impact is considerable
fallout is significant
impact is remarkable
affected is significant
impact is noticeable
consequences is significant
influences is significant
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com