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IL-12 has a major impact in the modulation of cellular immune response mechanisms.
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The impact of specific miRNAs in the modulation of venom composition, and the integration of the mechanisms responsible for the generation and impact of these miRNAs on patterns of expression in the snake's venom gland, are further challenges for future research.
In order to address the impact of the modulation of PaCATB abundance and activity on aging we next determined the lifespan of the different strains under different oxidative growth conditions.
With respect to the impact of the modulation of BMP signaling in the nasal and temporal domain the new Figure 4 now provides compelling expression data that fully support the hypothesis presented in the manuscript (please see the revised Figure 4).
Several studies [ 19, 21, 22] have just analyzed the impact of the immunonutrition in the modulation of inflammatory response and immune function after surgical procedures.
The impact of specific miRNAs in the modulation of venom composition, and the integration of the mechanisms responsible for the generation of these miRNAs in the evolutionary landscape of the snake's venom gland, are further challenges for future research.
This is the first trial to examine the impact of the modulation of T-cell co-stimulation with abatacept in patients with early RA.
We therefore investigated the impact of the modulation of TG2 levels and/or activity on cartilage degradation in CIA rats and in invadopodia formation in FLSs.
In the present study, we investigate the impact of immune-regulatory mechanisms involved in the modulation of the immune response in PLP transgenic mice, a model of oligodendropathy-induced inflammation.
We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants).
In conclusion, our data demonstrate that remodelling of actin filaments and inhibition of actomyosin contractility can impact stem cell behaviour through the modulation of clonal conversion.
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