Exact(1)
We expected a positive impact for weight loss on HRQoL.
Similar(59)
A number of factors can impact readiness for weight change, including demographics (i.e. gender, race, education) [ 10, 11] or psychological factors (attitudes, beliefs, and intentions) [ 11- 14].
Recent efforts support the feasibility of weight loss interventions for African-American breast cancer survivors [ 31, 39, 40] However, studies were not fully powered and none examined the physiological impact of weight loss for African-American breast cancer survivors.
To further evaluate the contributions of weight loss, a regression analysis of the impact of weight loss for each outcome parameter combining all three treatment groups was performed post hoc (data not shown).
Following the initiation of the selected therapeutic option, Step 3 involves reassessment of the patient for the impact of weight loss on complications after equilibrium weight loss is achieved.
The total scores for the Impact of Weight on Quality of Life-Lite questionnaire showed improvements from baseline to week 26 for both groups [LS mean: EQW +6.2 ± 1.0 (95% CI, 4.2 8.2) compared with detemir +2.8 ± 1.1 (0.7 4.9 ], with significantly greater improvement in the EQW group versus the detemir group (0.7 6.1; P = 0.015).
However, these measures, for example, the Impact of Weight on Quality of Life Lite (IWQOL-Lite), tend be sensitive to large amounts of weight loss as would more likely be seen with surgical techniques developed specifically for weight loss in the morbidly obese (Kolotkin et al 2002; Kolotkin et al 2003).
This is the first study to examine the impact of weight change during NCT for TNBC.
The goal of this study was to examine the impact of weight change during NCT for TNBC on pathologic response and Ki-67 reduction.
Given the obesity epidemic in the United States and its adverse association with breast cancer outcomes, especially in the setting of a disease that is aggressive and lacks effective targeted therapeutic options, we sought to examine the impact of weight change during NCT for TNBC on Ki-67 and pathologic response.
The impact of weight loss on wealth was considerably less for black women and it appeared to make no difference for black men.
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