Sentence examples for immunological model from inspiring English sources
In conclusion, in this chemically-induced immunological model for inflammatory bowel disease we demonstrated an important role for tachykinin NK1 receptors, and its ligand substance P, in the development of colitis downstream from mast cell activation.
The proposed architecture consists of an immunological model at the micro-level to detect and identify computer pathogens (e.g. viruses and worms), and an epidemiological model at the macro-level to identify distributed attacks.
Thus, establishing vaccination with HCT/HHD/B7.1 as an immunological model for human colon carcinoma.
He also highlights the strong role of "exogenous genetic assault" in variation and in his immunological model of evolution.
One drawback of using bioluminescence in an immunological model is the introduction of potential novel tumor antigens.
Holden and colleagues have also suggested a causal immunological model in which a stress-related increase in TNFα results in decreased activity of tyrosine phosphatase and in a consequently diminished expression of the class-I MHC antigen on the surface of malignant cells, allowing transformed cells to escape detection by the immune system [ 38].
Immunological modeling provides useful insights throughout the pharmaceutical process, from early-stage drug discovery such as target prioritization to development efforts.
These studies also indicate a central role of CD4+ T cells in CD pathogenesis and point to B cells as important players, which is in accordance with the key steps highlighted by the immunological models of pathogenesis.
However, because our results are consistent with current TB immunological models, we think they are unlikely to be false positive findings.
Recently, immunological models have attracted more interest, focusing on the role of leukocytes in fibrosis.
The hypothesis generally fits with current knowledge about maturation and disorders of immune system e.g. dysregulation of T helper type 1 (Th2), Th2 and regulatory T cell pathways, although the immunological models are constantly being revised and refined.
