Exact(3)
Cytokines such as IL-1 and type I IFNs and lipid mediators, such as eicosanoids, play key roles in regulating the balance between host-detrimental and host-beneficial immune responses and as such represent important targets for immunologic intervention.
Early diagnosis has the potential to identify subjects before the complete loss of endogenous insulin production, with the theoretical potential to preserve the remaining β-cells through intensive diabetes management or immunologic intervention.
Another characteristic of PCa which renders it attractive for immunotherapy is that it is a relatively slowly progressing disease, allowing sufficient time for the immunologic intervention to take effect.
Similar(57)
Dr. McCarthy reviews current knowledge of maintenance therapy in the autologous transplantation context, with emphasis on immunologic interventions and immune modulation strategies designed to prevent relapse.
These novel strategies include nonimmunologic therapies, such as targeted preparative regimens and posttransplant drug therapy, as well as immunologic interventions, including graft engineering, donor lymphocyte infusions, T cell engineering, vaccination, and dendritic cell-based approaches.
Since CTLs have been shown to play a major role in the control of human immunodeficiency virus (HIV) and other lentiviruses [ 2, 3], measurement of their activity has become an important parameter for testing the efficacy of candidate vaccines and other immunologic interventions directed against these important agents of disease [ 4].
An increasing body of experimental evidence suggested that different HIV-1 subtypes might exhibit disparate biological behaviors, and might respond differently to diagnostic, immunologic and therapeutic interventions [5] [7].
Although immunologic effects of psychosocial intervention are studied in breast cancer, it is a particularly poor candidate for demonstrating a clinically significant effect because it is not immunogenic [ 17, 55].
Identifying a possible mechanism for increased adaptation of these bacteria to the human immunologic host defense system or human interventions such as anti-TB treatment is of the utmost importance.
Importantly, the 12-week intervention did not have any adverse immunologic effects in this patient.
While genes related to tumor growth and metastasis were downregulated by Tamoxifen in FO fed rats, our data also point to a potential immunologic mechanism of tumor escape from the combined intervention.
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