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One-dose programs provided low levels of protection, unless the vaccine was administered at the age of 12 months, and a waning immunity rate of 1% per year or less was assumed.
Across America, vaccinations have fallen below the acceptable "herd immunity" rate of 90percentt.
The immunity rate to varicella was high among HCWs (98.2%).
If the waning immunity rate is below 5%, age 50 seems to be the optimal age at vaccination.
WHO outlined that to achieve sufficient herd immunity a minimum immunity rate of 90% in children and 75% in adults is required [ 12].
With a higher duration of stable VE the impact of a varying waning immunity rate on ICERs by age at vaccination.
Similar(48)
As most populations have high pre-outbreak immunity rates (often around 0.80 [21], [21]), the actual herd immunity threshold is calculated as: Pre-Outbreak Immunization Coverage+VT.
The advance of the disease across the continent was fuelled by low immunity rates.
Measles virus is a highly infectious agent and will infect any population with low immunity rates.
A combined sensitivity analysis of varying waning immunity rates and durations of stable VE illuminated their combined impact on the optimal age at vaccination.
Ultsch et al. [ 39] also found a considerable impact when exploring the combined influence of varying waning immunity rates and durations of stable vaccine efficacy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com