Sentence examples for immune system abnormalities from inspiring English sources

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple immune system abnormalities, including production of autoantibodies that can lead to inflammation and tissue damage [ 1].

To examine whether bronchial hyperresponsiveness (BHR) in patients with chronic fatigue syndrome (CFS) is caused by immune system abnormalities.

Krause et al. [29] conclude that "Although various immune system abnormalities, involving both cellular and humoral aspects of the immune system, have been reported in children with autistic disorder, previous studies are largely association based, and, it remains difficult to draw conclusions regarding the role of immune factors in the etiopathogenesis of this neurodevelopmental disorder".

Nevertheless, research into immune system abnormalities in Rett syndrome has been surprisingly limited.

The pathogenesis of BD remains unknown but major determinants involving genetic and immune system abnormalities have been recently reported [ 20].

Within recent years, search for innate immune system abnormalities in rheumatoid arthritis (RA) has attracted considerable attention [ 1].

Studies indicate that the effects of a vitamin D deficiency include an elevated risk of developing (and dying from) cancers of the colon, breast and prostate; high blood pressure and cardiovascular disease; osteoarthritis; and immune-system abnormalities that can result in infections and autoimmune disorders like multiple sclerosis, Type 1 diabetes and rheumatoid arthritis.

Numerous disorders in the immune system and abnormalities in cytokine productions have been described in patients with SLE.

Autoinflammatory diseases are characterised by hyperactivation of the innate immune system and abnormalities in pro-inflammatory cytokine signalling.

They present with stark immune system developmental abnormalities, and develop a chronic multi-organ inflammatory syndrome with strong manifestation in the skin (hence the name of this mutation: chronic proliferative dermatitis (cpdm)) at about 4 to 6 weeks of age [ 40].

The pathogenesis of OM is multi-factorial with risk factors such as delayed development of the adaptive immune system, complement system abnormality, as well as other environmental and genetic factors playing an important role [ 6- 10].