The phrase 'immune induction' is correct and usable in written English.
You can use it when referring to a process in which the immune system is stimulated to produce immunity to a specific disease. For example: "The process of immune induction is necessary for developing immunity to a pathogen."
Some of these infiltrating cells could differentiate into DCs and may be involved in immune induction.
Further investigation is required to verify whether lymphoid foci exist in oral mucosa and what their roles are in immune induction.
In contrast to other mucosal tissues, which generally contain mucosa-associated lymphoid tissue (MALT) for local immune induction, the oral mucosa lacks such immunological structure.
Secretory pathway was location of the human construct that enhances immune induction and contribute to the efficacy of the vaccine candidate.
Interestingly, co-treatment with PEG-IFN-α significantly suppressed HCV DNA vaccine-induced T cell responses, but not antibody responses, which demonstrated that IFN-α could act as a negative regulator of T cell immune induction.
Our results provide valuable information for the design of an effective therapeutic regimen to treat chronic HCV infection and to understand the immunomodulatory roles of PEG-IFN-α in immune induction by DNA vaccination.
One goal of the methods that were tested and employed was to generate high levels of mucosal MPER-specific antibodies, as mucosal immune induction could play a key role in preventing HIV infection.
In a recent study examining the mechanisms of immune induction by buccal DCs following DNA vaccination, delayed antigen-presenting activity was observed in mice.12 Presentation of the antigen to CD8+ T cells was mediated mainly by buccal-derived iDCs, while Ln+ iDCs showed limited presentation.
Similar co-localization of DCs and lymphocytes in the lamina propria was also observed by another study.60 Based on these findings, the concept of oral lymphoid foci was established, suggesting that inflamed gingiva might serve as a site for immune induction rather than just an effector site during periodontitis.
However, little is known about translational changes that occur during immune induction.
This study defines a role of CD86 in CTL immune induction and raises, new questions about the presumed function of CD80 in the generation of antigen specific immunity.
