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These findings have transformed our idea of kinetochores from cytological features to immense molecular machines and now allow molecular interpretation of many long-appreciated kinetochore functions.
Integrated genomic characterisation of HBV and non-HBV-related HCC emphasised the immense molecular diversity of HCC closely related to aetiologies that could impact clinical care of HCC patients.
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Mitochondrial complex-1 (MC-1) inhibitors show immense promise as molecular targets for novel cardiac radiotracers.
Microsatellites have immense utility as molecular markers in different fields like genome characterization and mapping, phylogeny and evolutionary biology.
Motivation: Thermodynamics-based dynamic programming RNA secondary structure algorithms have been of immense importance in molecular biology, where applications range from the detection of novel selenoproteins using expressed sequence tag (EST) data, to the determination of microRNA genes and their targets.
Within any tissue the massive combined surface area of component cells results in an immense number of specific molecular interactions between cell membrane components and the Extracellular Matrix (ECM).
The predictable use of these supramolecules as analogues of biomaterials, semiconductor materials and as molecular motors is immense and would open up a new plethora of boron compounds and materials.
There are conflicting results regarding the use of rituximab in FSGS, and it has been unclear exactly how this drug achieves success in some patients, but not others [ 102, 103].> In the era of personalized medicine, identifying FSGS-causing gene mutations and investigating their underlying molecular mechanisms have immense potential for the development of highly-targeted therapy.
Advances in novel high-throughput sequencing technologies provide immense opportunities to explore the molecular basis of response to abiotic stress, especially resistance and signaling-associated genes in different species by either de novo assembly or direct mapping to reference genome, resulting in identification and analysis of global transcriptome [ 13, 15].
Overall around 100 new genes were identified from these four disease-related libraries, which could have immense value for future research of molecular plant pathogen interactions.
Although microbes are such an important group, the characterization, identification, and quantification remain an immense challenge even with the conventional molecular tools [ 8, 9].
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