Human immunodeficiency virus type 1 (HIV) and Plasmodium, the malaria parasite, each present immense disease burdens worldwide.
Plasmodium falciparum is the most deadly human malaria parasite, notorious for its immense disease burden, ability to persist in individuals for months if not longer, and rapid development of resistance to all currently available treatments [ 1– 4].
Despite the immense burden of disease, NCDs, defined here as cardiovascular diseases, cancers, chronic respiratory conditions, and diabetes (3), nonetheless present a public health opportunity to intervene, not just in disease treatment but at all stages of disease progression.
Noble metal, especially gold nanoparticles and their conjugates with biopolymers have immense potential for disease diagnosis and therapy on account of their surface plasmon resonance (SPR) enhanced light scattering and absorption.
A glance at this issue's contents confirms the immense diversity of disease emergence over time and place, from birds with flu and Helicobacter infections to drug-resistant HIV strains, from Nipah virus to Arcobacter, from dengue to ameba-associated pneumonia.
We devote these resources to immunization because of the devastating consequences of not vaccinating: preventable child deaths; the immense social costs of disease; the re-emergence of infectious diseases that were once under control; and the spread of diseases to countries and continents where they had been eliminated.
The immense importance of infectious disease imaging in small animal models is based on the fundamental necessity to study disease pathogenesis and host immune response as well as to assess therapeutic measures such as medications and vaccines, on a time scale basis on the same subject(s).
The economic impact of the disease is immense, causing many lost days of work and loss of tourism and investment.
Consequently, the societal costs attributable to cerebrovascular disease are immense and encourage the medical community to seek new therapies that can reduce stroke's frequency and impact.
Not so in Angola, where the burden of sickle cell disease is immense and accurate statistics are not even available.
Most people associate these slums and others like it with immense poverty, substandard housing, disease, and inadequate water and sanitation services.
