Sentence examples for immediately preceding step from inspiring English sources

To ensure that the active site of our model reflected the conformation of Rnl2 immediately preceding step 3 chemistry, TbREL1 active site residue R111 was given a conformation commensurate with its Rnl2 homologue, R55.

The conformations of the other TbREL1 active site residues were in close agreement with the conformations of the homologous active site residues of T4 Rnl2 immediately preceding step 3 chemistry and so required no further manipulation.

These two unique conformations illustrate the active site conformational rearrangements that occur as the complex proceeds from the step 2 product, immediately following step 2 chemistry, to the step 3 substrate, immediately preceding step 3 chemistry.

A model of the step 2 intermediate of TbREL1 in complex with A-form dsRNA was built in homology to chain B of the T4 Rnl2 crystal structure [Protein Data Bank (PDB) entry 2HVR], which captures T4 Rnl2 immediately preceding step 3 chemistry (13).

It can also be done before the preceding step.

This partial order of causality includes a number of intermediate steps between conscious knowledge and action, the step immediately preceding action being "discussion".

Dome traffics through the late endosome [34], and loss of the hrs gene, which acts at the step immediately preceding ept [reviewed in 42], blocks Dome trafficking and activation even in the presence of Upd [43].

The observed kcat/ KM O2) will approach the O EIE when the forward commitment, which is the ratio of the forward and reverse rate constants for disappearance of the species immediately preceding the rate-limiting step, is small as might be expected for the slower chemistry in FIH.

Because neither iAsIII nor MAsIII interfered with insulin signaling upstream of PI-3K (Walton et al. 2004), the present work focused on the signal transduction steps immediately preceding PKB/Akt phosphorylation, specifically, on the enzymatic system controlling PIP3 levels in insulin-activated cells and on PDK-1.

Two preceding steps to the mapping process were performed.

All the preceding steps were iterative.