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This suggests that HIF1α is an immediate surrogate marker of cellular oxygenation.
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Such studies are of utmost importance because they might demonstrate that a drug's immediate impact on surrogate markers is not necessarily translated into reduced cardiovascular morbidity and mortality in the long term.
Only become a surrogate for immediate family if both the intended mother's egg and the intended father's sperm are used.
However, unlike tumour response criteria in unresectable cancer, no reliable surrogate markers permitting the immediate assessment of the efficacy of chemotherapy have been developed so far.
This was observed while the immediate post-ischemic flow increase, a surrogate for microcirculation, remained similar whatever the heart ischemic status in these diabetic patients.
Do not become a traditional surrogate mother for an immediate family member, such as a parent or sibling, since doing so would result in inbred genes.
Humanitarian organizations provide different services including education for refugees as a "surrogate for the state" in several immediate refugee-hosting countries like Jordan, Lebanon, and Iraq during the Syrian refugee crisis.
The potential of a surrogate marker assay that permits the immediate assessment of therapy-induced cytotoxic effects on occult metastatic cells is therefore evident.
Gestational surrogacy is the fastest growing segment of third-party reproduction in the this country and any such regulation will have an immediate impact on both agencies providing access to surrogates and the fertility centers providing medical services.
Such a process is unprecedented, and would allow simple organometallic reagents and simple amines to be the immediate precursors that are combined (along with an SO2 surrogate) for the proposed sulfonamide synthesis.
And it raised immediate suspicions that the attack might have been a way for surrogates or supporters of Mr. Perry, the Texas governor, who has stumbled in recent weeks, to gain ground by raising religious concerns about Mr. Romney.
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