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The laminar imbalance of COMT expression, which presumably leads to imbalance of dopamine availability at the synaptic level, may contribute to dysregulation of pyramidal neuronal circuitry in the prefrontal cortex, albeit to a relatively small degree.
Disease states, gender differences, electrolyte imbalance, energy availability and use, autonomic control, circadian changes (Jeyaraj et al., 2012), etc. all need to be incorporated into the computational models of the future, and used for cardiac safety testing.
Cuprizone exposure causes oligodendrocyte loss and demyelination and slow repair (left panel) because of OPC depletion, imbalanced growth factors, and low local availability of cholesterol.
But not all inputs were an improvement on 2010: fuel was still well below requirements; availability of crop protection chemicals did not improve; fertiliser, though up overall, was hugely imbalanced.
But the relationship is imbalanced.
Britain is imbalanced.
His body is imbalanced.
You're imbalanced.
It's wonderfully imbalanced.
Use an imbalanced set.
Both drought and aridity indicate imbalance in water availability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com