As the number of centromeres determines ploidity, a parallel rationale would be to relate imbalances relative to the largest identified population and therefore center this population at M = 0.
Overall, comparative analysis of the primary tumor and the serial passages of the orthoxenograft models indicated that, on average, < 7% of the orthoxenograft genome presented structural changes (copy number alterations and allelic imbalances) relative to the primary tumor.
Analysis of a number of other genes that are strongly and specifically expressed in tumour over normal lung, including SERPINB5, TERT and PRAME, showed marked allelic expression imbalances in the tumour tissue in the context of balanced or only marginally imbalanced relative allelic copy numbers.
However, as the ROC curve is sensitive to class imbalance, the relative position of the ambient and intimate networks is more relevant than the actual shape of the curves.
Rather, if protein expression were to be uniformly reduced, imbalances in relative protein levels should persist.
The absolute transcript level failed to resolve potential imbalances in relative allelic contribution to the total expression.
Integrating the above findings, it is plausible that development/function of language-related circuits in the human brain could be disturbed by imbalances in relative functional dosage of FOXP2 and FOXP1.
Many intense and fertile partnerships, whether creative or romantic, suffer from an imbalance in the relative importance that the respective partners attach to the partnership, to its history and its very existence.
The main reason for aerodynamic imbalance is a relative deviation of the pitch angles of the blades.
Please note that TDA-EDE and EDE achieve better performance than CRLB for I/ Qimbalance estimation with relative low SNR when validation according to practical range of I/ Qimbalance is performed.
