Sentence examples for imbalance profile from inspiring English sources

The pathogenesis of dengue virus infection leading to severe bleeding is complex but the major mechanisms involved can be summarized as platelet consumption, endothelial cell damage, imbalance profile of cytokines and chemical mediators, and suppression of hematopoiesis15.

Additionally, adenocarcinomas of the prostate were put in a separate group, due to the previous observation of specificities in the imbalance profile (e.g. overall lack of 1q gains).

Our study demonstrates the potential clinical diagnostic utility of genomic imbalance profiling in VSD patients.

The best differentiation between de novo and recurrent tumours up to now has been given by allelic imbalance profiles.

We use a dataset consisting of 5020 CGH samples (i.e. cytogenetic imbalance profiles of tumor samples) taken from Progenetix.

For the generation of overall genomic imbalance profiles, probabilistic thresholds of 0.13/-0.13 were used for genomic gains and losses, respectively.

This study attempted an overview of chromosomal imbalance profiles in epithelial neoplasias, based on a large collection of case-specific chromosomal imbalance data from published chromosomal CGH experiments.

Visualization of genomic imbalance profiles was performed by custom Perl routines using the GD.pm interface [ 38] to the GD graphics library [ 39].

Interestingly, in both unselected renal carcinomas as thyroid neoplasias, the average imbalance profiles included frequent gains on chromosomes 5, 7 and 12, while lacking the dominance of gains 1q and 8q found in most other entities.

However, the best differentiation between de novo and recurrent tumours to date has been given by allelic imbalance profiles that result from LOH and tumour heteroploidy as measured by aCGH [ 10, 12, 13, 16].

For model development and testing, we choose one hematopoietic (MCL) and one solid tumor entity (BLCA) due to their overall intermediate genomic complexity, without consideration of their previously established genomic imbalance profiles or CNA subset analysis.