Sentence examples for imbalance index from inspiring English sources

To study the feasibility of the crossover trial design and the minimal imbalance index random distribution method in the clinical small-sample-size randomized controlled trial (RCT) research of thalamic pain treated with acupuncture under the guidance of evidence-based medicine (EBM).

The imbalance index Ln β was significantly higher than 1 in all samples (Table 5), suggesting that V. inaequalis populations have recently expanded following a bottleneck [63].

The imbalance index also indicated that all populations experienced genetic bottlenecks prior to expansion [63], with the bottleneck event being most ancient in Eurasian than in non-Eurasian populations.

We used three different approaches to infer the demographic history of V. inaequalis populations: the test for expected heterozygosity excess/deficiency implemented in the Bottleneck program [28], the imbalance index Ln β [63], and the interlocus g statistic [65].

The deviation between the two estimators, measured by the imbalance index β (equation 7 in reference [64]), can be used to detect population expansion: Ln β is expected to be negative for populations that have recently expanded from equilibrium initial conditions and positive for populations that have recently expanded following a bottleneck.

We focused on a classical imbalance index, the index.

The strong current bottleneck (Fig. 3B) and past important expansions (Fig. 2B,D,F) resulted in highly significant imbalance indices and were well detected.

On the contrary, except for slow growth (Fig. 2A), using imbalance indices did not allow the currently growing populations (Fig. 2C,E), or the transient past increase of population size (Fig. 4) to be detected.

Conversely, assuming SSM in the analysis of data that were generated under a more complicated mutation model led to an overestimation of ancient population size and suggested the false detection of a current bottleneck, as predicted by the behavior of imbalance indices.

The β-imbalance index, as well as 95% confidence intervals, were estimated using a SAS program written and run by T. Lehmann [ 65].

The β-imbalance index is based on the imbalance between the variance in allele size and heterozygosity at a locus [ 62].