A 5th-year radiology resident and a senior radiologist with 35 years of experience in head and neck imaging read the high-resolution T2W gradient-echo sequence, blinded to the results of the T1W contrast-enhanced sequence.
In brief, this involved amplification and subsequent fragmentation of genomic DNA, followed by hybridization of this fragmented DNA to the BeadChip, then an extension step and finally imaging to read the chip (19).
Ignorance of these pitfalls directly affects the quality of the imaging read-out, leading to trial failure, particularly when imaging is a primary endpoint.
This study demonstrated the feasibility of using a dual PET tracer strategy using EGFR-targeting [methyl-11C]-ZEGFR:2377-ST-CH3 followed by the size-matched control [methyl-11C]-ZTaq:3638-ST-CH3 to study EGFR levels and examine underlying factors contributing to the imaging read-out.
All images were analyzed by an experienced investigator at the core CIMT imaging and reading center using in-house developed computerized automated edge detection software employing subpixel interpolation (Patents 2005, 2006, 2011) [ 19].
The diagnostic workup in dementia includes brain imaging with reading focussed on signs of cerebrovascular and neurodegenerative disease.
Retinal imaging research and reading center.
The versatility of the instrument is demonstrated by imaging cells and reading out a DNA-chip.
AG participated in protocol design, imaging acquisition, and reading results analysis.
