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Chief executive Matt Tee said: "When the current regulations were drafted nearly four years ago, it was difficult to imagine the developments that would take place in digital publishing, with some publishers having numerous editorial bureaux across the world focused on different audiences in different time zones.
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I think, truthfully, it would be hard to imagine the development of anything other than a kind of narco-state that is run by warlords and gangs and drug lords.
He told me his work was about "the possibility of the impossible", and that it made a pact with the reader to imagine the development of an idea, however absurd its premise.
It is also possible, however, to imagine the development of more sophisticated subscription models.
Nanomarkers designed to home in on specific molecular targets have enabled imaging techniques to be used not only to study the pathophysiological mechanisms of atherosclerotic disease but also to diagnose such disease, and have made it possible to imagine the development of a form of nanomedicine based on administering treatment that can target a single cell type.
Here's how I imagine the development of this show went behind the scenes at Netflix: People search for True Blood on Netflix in droves and are disappointed to find it's not there; people rent a lot of Twilight; people rent a lot of procedural dramas; vaguely sexy stuff does well, and viewers love Famke Janssen.
I couldn't even begin to imagine the development and success that would be missed if the program didn't exist.
In addition, it is also a priori difficult to imagine the development inhibition mechanism involving both secretion of a small compound and immunity to this compound to have resulted from a loss of some gene(s).
It is interesting to note that some of the pharyngeal gland defects present as branching of the gland projection; one can imagine the development of more elaborate branched structures by alterations in local mechanical constraint.
With respect to the overlaps between the sets of significant targets of a TF in different tumor types, one can imagine the development of an 'index of similarity' between tumor types of different origin driven by alterations of the same gene, based on the overlap of their oncogenic signatures.
Svante Arrhenius could not have imagined the development of micromanipulation techniques that allow measurement and control of piconewton size forces and nanometer size displacements with time resolution as short as a millisecond (see Figure 9).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com