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The Rotterdam Study research lines currently applying imaging within the Population Imaging Unit are those on neurological diseases and cardiovascular diseases.

From August 2005 onwards (RS-II-2 and onwards), brain imaging in the Population Imaging Unit is performed in all study participants without contra-indications in the context of the Rotterdam Scan Study.

Main objective for the Population Imaging Unit with respect to brain imaging is therefore to identify and quantify brain imaging biomarkers that mark the development of neurodegenerative and cerebrovascular disease.

The main imaging modalities that are currently being applied in the Population Imaging Unit are multidetector computed tomography (MDCT) and magnetic resonance imaging (MRI).

The Population Imaging Unit within the Rotterdam Study aims to assess imaging biomarkers of disease in a pre-symptomatic phase at the population level.

New developments to be expected within the Population Imaging Unit are on the one hand implementation of new imaging methods and on the other hand to integrate imaging data with other available data such as genetic data.

In the CONFIGR algorithm, the smallest independent image unit is the visible pixel, whose size defines a computational spatial scale.

In the scaling process of the scaling factor which is [0.4, 2], except for the special conditions, the image unit circle radius obtained will not change.

State-of-the-art electron beam analyses with atomic-scale resolution have imaged unit cell structure of the (100) [001] dislocation to form SGBs, as well as high-angle incoherent SGBs in deformed Opx porphyroclasts in mylonite.

By using "Osiris" software (Digital Imaging Unit, University Hospital of Geneva, Switzerland), regions of interest were selected on both right and left sides, and non-parenchymal pulmonary structures were eliminated from the regional analysis [6].

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