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In this article we investigate two-level split-plot designs where the sub-plots consist of only two mirror image trials.
As discussed, we were able to use liberal or stringent criteria for our classification of detection and location accuracy on the manipulated image trials.
The full horizontal lines on the bars represent chance performance for each manipulation type based on subjects' responses on the original image trials.
To determine how each factor influenced subjects' performance on the manipulated image trials, we conducted two generalized estimating equation (GEE) analyses one for accuracy on the detection task and one for accuracy on the location task.
These AS image trials were intermixed with other trials, including ones for which correct choices were available.
The three previously used sets of captions were reassigned to image trials, sentence trials, or appeared for the first time in the questionnaire, with set assignment counterbalanced across participants.
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They will be issued later this year and are certain to be influenced by the Image trial results.
A total of 755 patients took part in the Image trial, led by Professor Paul-Peter Tak from the University of Amsterdam in the Netherlands.
Disease activity at baseline in the rituximab database (IMAGE trial of early rheumatoid arthritis).
For the IMAGE trial, RF seronegativity at baseline was allowed only if there was evidence of erosive disease.
23 The IMAGE trial was conducted in MTX-naïve patients with early disease, and many alternative treatment options are available for these patients; therefore, following a spontaneous report of a case of PML in a rituximab-treated patient not previously exposed to biological treatment, 24 the sponsors took the decision to discontinue dosing with rituximab in the IMAGE trial.
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