Furthermore, the high scatter component intrinsic of 90Y PET imaging may negatively affect image quantification.
The image quantification was done using Icys research imaging cytometer (Compucyte, Westwood, MA, USA) and analysed as described in http://www.compucyte.com/cellcycle.htm.htm
Compared with SPECT, PET offers the potential for better spatial resolution, a more accurate image quantification, and a wide range of possible imaging probes.
Image quantification and information extraction remain to be a challenge for integrating imaging and omics information.
However, image quantification will also be affected by other factors.
Porosity was mapped by employing X-ray CT (computerized tomography) scanning and image quantification.
Accurate image quantification can improve the calculation of the activity, %IA/g and absorbed dose.
Hence, the specific activity of the radioligand has a profound effect on image quantification.
For retrospective image quantification, age-specific 3D-printed phantoms were manufactured and calibration measurements were performed.
This need will drive research leading to improvements in image quantification and to more sophisticated image analysis.
A calibrated source of 123I was placed within the SPECT field of view in order to facilitate image quantification.
