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Although the achieved sensitivity was sufficient for OCT imaging with deep image penetration, as shown in Fig. 13, the reduction of 10 dB from that expected for the shot-noise limit should be improved.
By combining the advantages of ultrahigh speed swept source/Fourier domain OCT at 1-µm wavelengths, volumetric imaging of retinal structure with increased image penetration and high sensitivity to flow velocities in the central retinal vessels, future investigations could enable time-resolved imaging and quantitative measurement of retinal blood flow.
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Imaging penetration using fluorescently labeled active agents also yields accurate lateral and depth spatial information; however, the fluorophore may alter penetration mechanisms.
The solid lines represent quadratic fittings, where it can be seen that the velocity profile takes on the shape of a parabola demonstrating a laminar flow mode [ 28]. Figure 6(g) shows a half parabola because only the top half of the cross-section of the blood vessel was imaged due to limited imaging penetration.
Choosing a volume image out of the OCT video of porcine trachea recorded at a rate of 11 volumes/second with a voxel size 256 (axial) × 256 × 256 (lateral), deep image-penetration was demonstrated.
Double penetration cowgirl style!
For biological imaging applications, light microscopy always compromises between image quality, penetration and non-invasiveness.
We were able to image the penetration of NPs in these tissue sections for the first time.
These projectiles of passion are usually depicted piercing the heart, a graphic image of penetration reminiscent of the arrows that the Hopi shoot into rounded, vulvic bundles of corn as a ceremonial gesture of fertility.
Sound frequency, image contrast, penetration depth and image size were adjusted to obtain optimal visualization of the left ventricle.
e, f Dark-field images showing penetration of 50 nm GNPs through MDA-MB-231 and MCF-7 tissues, respectively Open image in new window Fig. 6 Spectral mapping of size-dependent NP penetration through tissue.
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