The acquisition time of one slice was 47 seconds with a FOV of 380 × 380 mm, an image matrix of 352 × 352, and a slice thickness of 5 mm.
All PET images were attenuation-corrected and an image matrix of 400 × 400 pixels was used for iterative image reconstruction.
All PET images were attenuation-corrected and an image matrix of 400 × 400 pixels was used for iterative image reconstruction (voxel size 1.565 × 1.565 × 0.6 mm) based on the syngo MI PET/CT 2009C software version.
All the images were reconstructed using Dynamic Row-Action Maximum Likelihood Algorithm (DRAMA) with an image matrix of 128 × 128, resulting in a voxel size of 4.0 × 4.0 × 3.25 mm3.251].
PET data were reconstructed using a transaxial image matrix of 256 × 256 and an ordered subset expectation maximization (OSEM) algorithm taking advantage of time of flight information and modeling the system response.
Findings from this study are based upon an image matrix of 256 × 256 voxels, whereas other centres may use different parameters such as 200 × 200 or 400 × 400 voxels, which are common choices on the mCT due to the system's intrinsic 400 × 400 matrix.
The CT images were reconstructed using cone-beam reconstruction with a Shepp filter with a cutoff at the Nyquist frequency and a binning factor of 2, resulting in an image matrix of 480 × 480 × 632 and a voxel size of 0.206 mm.
The T2* value of the tissue has been determined by employing a range of TE values from 20 60 ms with a relatively low image matrix of 128×128 and the resultant in-plane resolution was 400 µ which is two times lower than the one employed for detecting cerebral haemorrhage.
For high-resolution structural imaging with whole-brain coverage, an additional strongly T2 weighted 2D turbo spin-echo sequence was acquired (RARE factor 16, TR = 8 s, effective TE = 56.44 ms, 2 averages, 13 coronal slices with an image matrix of 128×128 were acquired, FOV = 1.8 cm×1.8 cm, slice thickness = 0.5 mm, interslice distance = 1 mm, overall acquisition time of 2 min).
All PET images are attenuation corrected and an image matrix of 400 × 400 pixels is used for iterative image reconstruction.
