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The time series indicated the temporal position of: display of image for each of the 4 conditions (Go Win, Go Avoid, No-Go Win, and No-Go Avoid), the onset of the circles (for each Go and No-Go trials in which subjects correctly responded), display of outcomes for the 3 possible outcomes (win, neutral, and loss), and display of image for trials with an incorrect response.
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Figure 7 shows the localisation data calculated using an ROA as a function of detection performance (collapsed across radiologists and images) for trials on which detection plus localisation were correct (blue bar), the additional localisation correct trials produced by including a ROA (dark grey bar) and detection only trials on which localisation was incorrect (light grey bar).
An averaged image from the first five frames of each trial was then used as a reference image for that trial.
Single trial models were generated to estimate the response to each individual trial (N = 252 per participant), resulting in a beta image for every trial.
This noise level was then used for the low salience images in combination with the original images for the trials required to estimate the SIC.
Computer aided detection (CAD) of lesions in the lung is a good example of advanced image processing that can enable superior and more efficient analysis of images for clinical trials [ 22].
The analysis resulted in 8 activation estimates (beta-images) for each trial type, 1 per run.
The remaining two sessions required first the estimates of each sensor's psychophysical thresholds at 82% accuracy by manipulating the amount of pink noise added to the image (120 trials for each sensor for each day) followed by trials required to estimate the SIC (2160 trials in total).
Each grayscale image was presented for an average of 15 trials, and each color image for an average of 22 trials.
Recent NCI guidelines spell out specific protocols for patient preparation and all aspects of image acquisition for any trials involving this modality [ 20].
Participants searched the image for a change or until 40 s had passed, at which point the trial was terminated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com