One cranio-caudal image was digitized for each subject, using a Lumisys 85 digitizer, and measured by one observer (NFB), in sets of approximately 120, with equal numbers of randomly ordered cases and controls.
If this information was not given in sufficient numerical detail in the meta-analysis, we sought to complement it by extracting information from the meta-analysis forest plot using software for image digitisation (Engauge Digitizer 4.1).
The time stretch allows the image to be digitized by a conventional electronic digitizer.
Results: In March 1997, the clinic directly began processing oral and maxillofacial radiographs with digital image acquisition devices or converted them into proprietary digital format with a film digitizer.
Measurements were performed semi-automatically using a digitizer and image analysis software (Osteomeasure, Atlanta, GA, USA).
It is possible that differences in film digitizers and/or digital mammographic image acquisition systems between studies could influence RTA, particularly for the gray-level magnitude-based features which have been previously shown to be sensitive to the effects of variable gain [ 48].
A ColourView III digital camera (OSIS FireWire Camera 3.0 digitizer) was used to capture images in conjunction with CELL* Imaging software (Olympus Cell* family, Olympus Soft Imaging solutions GmbH 3.0).
In order to evaluate the change of JSW, PA radiographs were converted to digitized images using a laser film digitizer LD-55000, Konica Minolta MG, Tokyo, Japan), which can scan films at a maximum resolution of a 50-μm focal spot with 256 levels of gray.
They have also compared the 8 and 14 bit-depth images by using a second 14-bit digitizer (200MS/s, Gage Applied Technologies, US) and showed that the 8-bit image was comparable with the 14-bit image, however the comparison was made without a quantitative analysis.
When raw glucose data were not available, printed glucose profiles were scanned and digitized with Engauge Digitizer software (http://digitizer.sourceforge.net) to retrieve numeric data.
