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It's not considered the first monochrome because it is still a black square on a blank background--an image differentiated from a field.
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As an example of this case, we have imaged differentiated mouse embryonic stem cells (ESc), as discussed in the Supporting Information Figure S15.
Currently, we have 365 images for differentiated cells and 36 images for stem cells registered in the database.
Light-microscopic images of differentiated MCs from representative groups are shown in Figure 7B and 7D, respectively.
(F) Phase contrast images of differentiated stem cells on a flat RGD-treated gold surface (left) and on RGD-treated Au NWs (right).
In SHaSM, the dimer can be easily and visually seen from the images and differentiated from the background of individual NCs.
Imaging of differentiated HL60 cells (which mimic neutrophil behaviour and show both plaques and cytoneme projections) expressing the filamentous-actin probe LifeAct revealed that these structures were composed of F-actin (Fig 3D).
This merger is a good example of how companies often try to differentiate their brand based on corporate social responsibility, believing the differentiated image will lead to a competitive advantage.
What we can also consider is what would happen if we looked at the differentiated image.
However, my research sounds an alarm bell for those efforts to create a differentiated image that is unfortunately based on weak customer and employee identification.
And so either viewed as a filter, or viewed intuitively, we would expect that the differentiated image would, in fact, attenuate this slowly varying background and amplify the rapidly varying edges.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com