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These principles are illustrated in the development of IMRA products like Madeglucyl, a treatment for diabetes management that was developed from a traditional remedy.
This pattern of ADL follows the hierarchy of early, mid and late loss ADL originally outlined by Katz [ 32] and developed further in other studies since [ 18, 33- 35], and illustrated in the development of the MDS-ADL scales [ 29].
This is well illustrated in the development of the reproductive spores, as they are called.
This is also illustrated in the development of the grains of the dust-like pollen, which is shaken out of the flowers of the higher plants, or those which have obvious flowers.
These methods will be applied and illustrated in the development of algorithms for mixed-integer linear programs, mixed-integer convex programs, nonconvex programs, mixed-integer nonconvex programs, and programs with ordinary differential equations embedded.
Here, three surface-engineering strategies for microarray design are described and are illustrated in the development of a peptide chip for the quantitative analysis of kinase activity on solid support.
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To illustrate, in the development of the Avaluator, Haegeli and McCammon [8], [17] assumed, without stating so, that missing values occurred due to some purely random process (i.e., in technical terms, were missing completely at random, [13], [14], [18]), that is, that the 82% of accidents they excluded from their analyses were no different from the 18% of accidents that they retained.
The cluster analysis illustrated differences in the development of maximum isometric force between vibration training and traditional strengthening.
This is perhaps best illustrated in the twentieth-century development of the nutritional sciences, where increased attention to caloric energy and the discovery of vitamins shaped food consumption and labeling in the United States.1 Such studies not only affected how humans ate; they also influenced the foodways of the nonhuman animals integral to human food systems.
The second approach - the design of therapeutic strategies from knowledge about particular gene defects in individual tumours - is illustrated by the development of poly ADP ribose polymerase (PARP) inhibitors for breast and ovarian cancers in patients harbouring BRCA1 or BRCA2 mutations.
Therefore, this approach to annotation is frequently inadequate as exemplified in the literature [ 20- 22] and illustrated by the development of alternative paradigms for functional annotation [ 23- 26].
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