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Immunohistochemistry for PAR illustrated few positive cells in the ONL of untreated wt situation (0.1% ±0.02 SEM, n = 3), larger numbers of positive cells in zaprinast treated wt (0.7% ±0.07 SEM, n = 5) and rd1 ONL (1.3% ±0.3 SEM, n = 3), and very few positive cells in untreated (0.05% ±0.01 SEM, n = 3, p<0.05) and zaprinast treated PARP1 KO retinae (0.1% ±0.02 SEM, n = 3, p<0.05) (Fig. 3F J).
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CEO of Professional Science Editing for Scientists @ prosciediting.com