Nevertheless, I do critically reiterate that I believe the use of fluorescein outside of studies to be premature and requiring further investigation in a complex field in which histology, timing, dose, illumination, tissue perfusion, and edema play a role, with a marker of blood brain barrier integrity that offers a tissue signal that is not simply binary.
This accumulation also occurred with similar timing during continuous light illumination, which corresponded to 36 38 h after the onset of the first light illumination (Fig. 1A).
The effect of illumination varies depending on its timing within the dark period.
It is only through the ethnography that we can speculate that the timing of the illumination was considered important in Mayan society.
We next examined the most effective duration and timing of laser illumination, relative to electrical stimulation, for suppressing synaptic transmission.
To address the effective timing of laser illumination, we maintained a constant duration (100 ms), but varied the time, relative to the electrical stimulation, for delivering the illumination.
Light bars and circular illumination regime indicators show the timing of treatment and sampling in the day (Figures 4, 6 and 7).
While further investigations will be required to identify the sources of inter-individual variation in amplitude and timing of the diurnal post-illumination pupil response function, the general relationship between this response and the DLMO was consistent across all observers.
The amplitude and timing of the ipRGC controlled post-illumination pupil response relative to salivary melatonin shows individual differences (Table 1).
Removing leaves around the clusters is a powerful and widely-used strategy to control berry illumination and temperature, although the impact depends on the timing of treatment.
