Sentence examples for illuminated a role from inspiring English sources

Our crosstalk study illuminated a role of a positive feedback loop in sustaining NF-κB response; where non-canonical LTβR signal prolonged canonical TLR4 response by targeting RelA induced p100 for the generation of RelA p52 NF-κB dimer.

It establishes a time course of the relationship between the emergence of metabolic dysfunction and visual decline in three diabetic models in the same mouse strain, it illuminates a role for mitochondrial dysfunction in the pathogenesis of diabetic visual complications and it demonstrates a clinically feasible approach to treating it.

In the case of PPARγ, use of a transcriptional repressor designed to downregulate the expression of two PPARγ isoforms allowed "mutation-free reverse genetics" analysis that illuminated a unique role for the PPARγ2 isoform in adipogenesis (Ren et al., Genes Dev 2002 16:2002 16

Several animal models have illuminated a direct role of culture environment on many facets of embryo viability and long-term development.

Moreover, previous studies have illuminated a pivotal role of the p38 mitogen-activated protein kinase (MAPK) pathway during GTP-mediated erythroid differentiation of K562 cells with the accumulation of HBG mRNA (Osti et al, 1997; Moosavi et al, 2007).

The latter results illuminated an important role for the primary PP2A methyltransferase in survival, but yeast lacking the major PP2A methylesterase (Ppe1) were without apparent phenotypic defect [26].

Further characterization of proximal limb development and segmentation in N-Myc and dcko mutants may help illuminate a potential role for N-Myc in retinoic acid signaling and how undifferentiated mesenchyme contributes to the regional specification and growth of the developing limb skeleton.

Combined, these findings illuminate a novel role for ubiquitin in controlling Ras activity, in addition to regulating its spatial location.

The current study also illuminates a critical role for the C-terminal residues of Rpn11 in docking of module 2 components.

Finally, the result that the Hippo-kinase activity regulates a caspase, which cleaves Brm and that the Cleavage resistant Brm illuminates a regulatory role for Brm is very interesting.

A recent study has illuminated a pathophysiological, eCB-independent role for MAGL as well.