The pooled baseline demographics, psychiatric history, and disease severity of patients are shown in Table 2. Patients were chronically ill, diagnosed predominately with schizophrenia, and exhibited an average illness duration of about 16 years.
Age, duration of illness, duration of hospitalization, years of education, body mass index, neurocognitive function, drug-induced extrapyramidal symptoms, involuntary movements, psychiatric symptoms, and dose equivalents of antipsychotics and anticholinergic agents were used as index factors.
Migraine-specific variables included migraine subtype, age at onset, duration of migraine illness, duration of migraine attacks, migraine attack frequency, headache intensity, headache disability, presence of cutaneous allodynia, presence of depression, migraine-associated symptoms, and use of headache medicine.
This finding is remarkable, as the DSM-IV criteria, contrary to the new criteria, require illness duration of least 6 months.
Furthermore, there were no correlations between GSH levels and clinical variables (age, education, estimated IQ, age at onset of illness, duration of illness, GAF, and amount of medication) in the subjects.
TBM was defined as "possible" in patients with at least four of the following: a history of tuberculosis, predominance of lymphocytes in the cerebrospinal fluid, illness duration of more than five days, a ratio of cerebrospinal fluid glucose to plasma glucose of less than 0.5, altered consciousness, yellow cerebrospinal fluid, or focal neurological signs.
We also evaluated the influence of the illness duration on the accuracy of the NS1 Ag-based tests.
All four measures of diagnostic variation are very strongly associated with numbers-of-hospitalisations and less so with duration-of-illness, duration-of-hospitalisation and with year-of-first-admission.
Patients with a shorter duration of illness were more likely to be seronegative; 14 (30.4%) of 46 patients with a duration of illness <14 days, 8 (9.8%) of 81 patients with illness durations of 15 and 21 days, 5 (7.8%) of 64 patients for those with 22 and 28 days, and none of those who survived for >28 days (χ for trend = 20.5, p = 0.00001).
Data were also analyzed regarding major illnesses; duration of respiratory, hemodynamic or renal support; length of stay in ICU, hospital; adverse events.
It is appreciated that the sensitivity of clinical predictors for influenza varies depending on a multitude of factors including the prevalence of disease, age, underlying illnesses, duration of symptoms prior to consultation, and the vaccination rate in the population tested.
