Suggestions(1)
Exact(34)
The Phase II portion of this study evaluating orteronel with concomitant prednisone is ongoing.
Based on these results, the phase II portion of the study was initiated (Table 2) [ 73].
The phase II portion of the study then proceeded using dose level 1.
The phase II portion of the study included 48 patients, who were treated with 75 mg m−2 of irinotecan.
Once the MTD was determined, the phase II portion of the study was conducted to determine the activity of temsirolimus.
Once the MTD and the recommended dose were defined, patients were accrued to the phase II portion of the study.
Similar(25)
While phase I and phase II portions of the CHHiP trial [ 50] have estimated toxicity, the UK Medical Research Council (MRC) phase III noninferiority study will include over 3000 patients in a 3-arm design to extrapolate the isoeffective dose for complications and address whether HFRT is equivalent to CFRT.
However, we are the first to report the promising result of the phase II portion for combination therapy with CPT-11 and S-1, in detail.
Among the 25 patients in the phase II portion, the dose of paclitaxel was reduced in three patients within one cycle because of neutropenia and thrombocytopenia.
In the phase II portion, the incidence of the most common toxicities (grade 3 or 4) was 14% for neutropenia, and 10% for diarrhoea and anorexia.
The phase I portion of the clinical trial is completed, and the phase II portion evaluating the efficacy of combined imatinib plus chemotherapy is currently successfully enrolling.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com