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Immunostainings were run with known positive and negative tumor controls and were blindly evaluated by a pathologist who ignored sample identity.
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In the above sessions we ignored samples in which Δst≤0.
Therefore, conditional context is often ignored, samples are combined and similarity measurements are calculated across all samples.
We used only 125 NSCLC samples from the profile GSE11969, including 35 squamous cell carcinoma samples, 90 adenocarcinoma samples, and five normal samples, and ignored samples with other subtype.
We present and compare several analytical methods for comparing means from two-stage sampling: (1) simple ANOVA ignoring sample structure, (2) unit means ANOVA, (3) Nested Mixed ANOVA, (4) restricted maximum likelihood (REML) Nested Mixed analysis, and (5) REML Nested Mixed analysis with heteroscedasticity.
We stress that this is not strictly an assessment of statistical significance, as we are choosing to ignore sample size.
Indeed, when the proportional contributions to genetic diversity are estimated by ignoring sample sizes (PCunweighted), only the Siboney and Cr.
The consequence of ignoring sample size is that the magnitude of r 2 can be overestimated in samples of small size as a consequence of spurious associations.
The results section uses a graphical representation to make the discussion of the impact of ignoring sample design more accessible to non-mathematical readers.
When the proportional contributions to genetic diversity were estimated ignoring sample sizes (PCunweighted), Indicine, Creole6, Creole5, Iberian4, Creole2 and British breed groups ranked highest (7.715 < PCunweighted < 8.174).
The main aim here is to present - as clearly as possible for non-statistical researchers - the impact of ignoring sample design, and thus to contribute to improving data analysis practice in epidemiology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com