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The underlying consideration is that if we have a good understanding of in vivo contribution of elimination pathways based on clinical DDIs, the information can be useful in quantitatively assessing the risk of pharmacokinetic change with OI, since the expected change with OI in each pathway is theoretically equal to or less than the pharmacologic strong inhibition of the particular pathway.
Similar(59)
"We have a good understanding going forward.
"We have a good understanding," said Rooney.
We have a good understanding of patients' risk factors.
If we don't have a good understanding, we cannot say if all the activities, or all the activities and material, are for peaceful purposes.
"If you have a good understanding of the optical properties of a species, then you have the potential of developing an algorithm specific to that species," he says.
But the rule-based model can be a good choice if the researchers have a good understanding of the data and if the decision tree approach cannot capture certain patterns in the data.
"We don't have a good understanding of the air flow," Dr. Settles said.
"We chose to have a good understanding with them.
"Those who think we can defeat the U.S.A. do not have a good understanding of volleyball".
Then you have a good understanding of if there is a trend here.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com