We aimed to determine if there was a linkage between methylation and the observed changes in the zebrafish HCC gene expression, and to compare biological pathways represented by altered gene methylation in zebrafish HCC with pathways commonly altered in human HCC.
It is ironic because scientists increasingly believe there is a linkage between the prolonged dry spell and climate change.
There is a linkage between this war and the disease.
To have your project succeed, just add links between jobs too see if there is an important linkage between them.
If there is a need to have a functional understanding of QTLs, linkage mapping is more appropriate than association mapping.
QTLs are mapped by linkage to the molecular markers and if there is a significant statistical difference in longevity between genotype classes for a particular marker, one infers a QTL affecting longevity that is linked to the marker.
So, if there is a strong association in a well matched sample between a SNP and the disease, the best guess is that there is a causative allele tightly linked physically to (and in linkage disequilibrium with) the SNP.
Consequently, even if there was a causal linkage, the exposure-response relationship is highly non-linear.
If there is any linkage between low temperature and low snowfall it is probably because if you get the air coming up from the south in the UK it is warmer and hence moister, so you can convert more of that water into snow.
However, the ethical and legal considerations of the data usage must always be considered, especially if there is any linkage to other databases or information that could be used to identify individuals.
