"Parents say if there is published research that says three drugs work, I want my child to have three – not just one," said its chief executive, Alison Moy.
In contrast, a worst-case scenario would be that the aims were not completed and no papers were published, or, if there were published papers from the work, they appeared in subspecialty-level journals and had little impact on the initial goals of the previous application.
MUTYH defects were considered pathogenic only if there was published evidence of their pathogenicity.
A drug was only included in the training or active test set if there was published evidence of DILI with immune features (e.g., fever, rash, or eosinophilia), or if there are genetic associations with proteins known to activate the adaptive immune system.
Individuals reported to have two defects at MUTYH in the original report were classified as MM (defects were considered pathogenic only if there was published evidence of their pathogenicity), those with one defect as WM and those with no detected defect as WW.
Sure, I can check CLIO to see if there are books published in my area of interest, but it can be hard to tell from the title or subjects listed in a CLIO record whether a book is relevant to my research.
Under existing Italian law, unproven stem cell therapies can be administered on a case-by-case basis to patients with untreatable, severe illnesses who have no other options but only if there are enough published data on safety in internationally recognized journals and if therapies are prepared by authorized hospital labs under the Italian rules for the production of stem cells.
First, they would need to know if there are any published results on their candidates at any taxonomic level.
If there is an afterlife and theatre reviews are published there, the spirits of Anton Chekhov and DH Lawrence will be bemused to read about productions of plays they didn't know they'd written.
Business Secretary Vince Cable commented: "We will look carefully at the committee's final recommendations when these are published and if there is new evidence that blacklisting is continuing today, I will ask the appropriate authorities to carry out a full and thorough investigation". A Scottish government spokesman said: "We are totally opposed to blacklisting.
