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Some problems remain in identifying correctly which sequence reads belong to the individual tagged, particularly if single (one end) indexing is used.
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If every single one of them stayed on Centrelink benefits for the whole time it took to assess their asylum claims, it would cost about $500m a year – all of which would be spent in Tasmania.
If a single one of these things had happened on a previous President's watch, it would have been regarded as a major crisis for the White House.
"There would," she revealed, "be less negativity in society if every single one of us woke up with a smile on our face".
We knew that we would be in trouble if every single one of us did not perform but our inner belief meant that we did.
The United Nations would evacuate its advisers from Syria if a single one of them were killed, something that Assad or his extremist enemies could easily arrange.
And in Toronto, during these past few surreal days, it feels as if every single one of them is being tested out, repeatedly, by every single person in the city.
The children in Dinner at 11 were so remarkable that I wouldn't be surprised if every single one from a working-class background defies the odds against them.
"If every single one of those things is not in the settlement agreement, you'll either end up back in court or sucking it up and moving on," said Stacey Welsh, managing partner with Sovereign Wealth Management in San Francisco.
Imagine for a second if every single one of the 32 people killed in the recent suicide attacks in Belgium (or Pakistan, or Baghdad – the list is endless) were remembered in a similar way.
If every single one of their fans switched from ownership to streaming, the band would need at least 200 times as many new listeners to make up for the shortfall.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com