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Conversely, an amplified or deleted gene that is upregulated or downregulated only minimally, in a statistically non-significant manner in patient data can still function as a driver gene if it alters the expression of its network neighbourhood.
Mr. McConnell's personal battle matters beyond Kentucky if it alters the national agenda.
These are quite different questions, as teachers may perform better with a given qualification, but requiring that qualification may separately influence the overall effectiveness of the teacher work force if it alters who chooses to teach or where teachers choose to teach.
Synaptic plasticity of a given neuron's inputs is functionally effective only if it alters neuronal spiking, so that information is passed on to downstream synaptic targets.
Function of this 690-bp intron, i.e. whether it plays a role as an enhancer or if it alters tissue-specific expression, is of interest to us.
The motivation for eQTL mapping and eSNP analysis is that genetic variation is more likely to impact a disease trait if it alters gene transcription.
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Both churches have in the past said they might abandon the Boy Scouts if it altered its policy on gay members and leaders.
First, lithium, a selective GSK3 inhibitor, was administered to wild-type and Fmr1 knockout mice to test if it altered social behaviors.
In distinct if subtle ways, it alters calculations by the White House and its partisan adversaries concerning his foreign policy goals, domestic agenda and prospects for re-election.
If it only alters, leaving, as manifest convenience requires, the general organization of the polls to the State, there results a necessary cooperation of the two governments in regulating the subject.
If we apply the TPB to this scenario, we see that knowledge of genetic risk only motivates the obese patient to exercise if it significantly alters his attitudes and normative assessments of, or perceived control over, exercise activities.
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