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We crossed Pml−/− mice with Tsc2+/− mice to assess if: (i) loss of Pml impacted on kidney tumourigenesis by promoting further mTORC1 activation; (ii) loss of Pml was sufficient to tilt the feedback balance and promote Akt activation in conjunction with mTORC1 activation; (iii) compound Pml and Tsc2 loss would accelerate tumour initiation and/or progression in the kidney.
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If we can embrace that loss is loss; if I can sit across from my clients in the presence of their loss, with their loss, rather than comparing our losses then we are simply two mothers who have lost.
If I suffer a loss before I've saved enough, I am wiped out.
If I were describing losses in a particular battle, and I said that our losses were one to one thousand for the enemy, I would be mocked as a fiction writer.
"If I keep my losses at $7,000, I can sleep easily," Dahlman says.
If I'm sustaining losses of 70%, it means I thought about it but decided not to sell.
How could I mitigate the losses if I wasn't sure what those losses would be?
Others, especially those who described their visual field as significantly deteriorated, expressed a willingness to accept the risk of accelerated vision loss: "If I lose my sight, it's going anyway". P2 Patients also described factors that attenuated their risk perspectives.
I would be at a real loss if I couldn't do that.
The UK benefits from me being here – it will be their loss if I return home.
I do these in French as best I can, but if I am at a loss for words I draw.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com