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We provide the identity of clusters 'linked by annotation' as part of the XenDB output.
Allocation of clusters Clusters were allocated by two members of the evaluation team (ELMOdC and IVFvdB) who were blinded to the identity of clusters.
We do not think this happened because the investigators were blinded to the identity of clusters and did not know whether the intervention effect might differ by risk level or cluster size.
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(e) t-SNE plots showing expected identity of cluster groupings based on markers in (d) (Table S1, ambiguous data sets defined in Methods are shown in gray).
In each iteration of clustering, the identity of a cluster was determined by the rank of its median of H3K4me1/H3K4me3 ratios among all clusters.
No correlation was apparent between the identity of these clusters and their mode of regulation, i.e. G. metallireducens cluster 3 is classified as an E. coli-like cluster, and the other two do not belong to any identified class.
The chemical identity of metal clusters in NTs was confirmed by the local-probe energy dispersive X-ray (EDX) analysis (Supplementary Figs. 1 and 2).
What could be the identity of these clusters?
The study uncovers identity of ortholog clusters as possible signatures of pathogenicity or synergy in a mixture of bacteria.
The individual identity of the clusters that map to these categories should offer possible hypotheses that can be tested in our future research.
The allocation sequence, stratified by a service provider, will be generated in Stata V.13.0 85 by a statistician blinded to the identity of the clusters and not involved in the assessment or intervention delivery (PC).
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