For example, to identify unique EE responses, the 2417 differentially expressed TAM genes that satisfy the P1 t) > 0.9 and |fold change| > 1.4 were excluded from the 2657 differentially expressed EE genes (P1 t) > 0.999; |fold change| ≥ 1.5) to identify 240 genes unique to EE treatment (Fig. 8a; Additional file 4).
For example, laboratory studies identified unique weathering signatures for individual fungal species grown under sterile conditions with phlogopite mica, where each species exhibited specific growth patterns (e.g., branching on mineral surface, penetration of interlayer sheets) and biochemical weathering signatures when interacting with the minerals50.
The combination was for example used to identify unique major histocompability complex peptides that are recognized by T cell receptors [ 61].
Among the rice TE-related genes, PICKY 1.0 software, for example, was able to identify unique oligos for only a couple of hundred [76].
Metabolomics aims to identify unique fingerprints of specific injuries and functions, for example, diseases or effects of exposure to toxic compounds [ 82].
The drug control policy office is betting on stable isotopes to identify unique markers in marijuana, distinguishing it not just by geography but also by its cultivation method — for example, indoor versus outdoor.
For example, exploring the diffuse large B cell lymphoma cell lines, which are clustered within the plasma cell myeloma cluster, can potentially identify unique mechanisms and potential mislabeling.
And eTour lets us identify unique visitors.
To identify unique chemical entities.
In addition to the Canadian broadcaster example of re-identification through obituaries, another study presents an example of how obituary data was used to re-identify uniques in de-identified pedigrees [ 18].
In summary, we identify promising examples of unique gene expression responses which show in vitro in vivo similarities supporting the relevance of in vitro developmental models for predicting in vivo developmental toxicity.
