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The optimization allowed identifying the substrate interaction effects in a concentration range with a reduced number of experiments.
We suggest evaluation of the roles of other CYP3A genes in relation to ON and control groups, with clearly identifying the substrate regiments of the gene products in the future.
Similar(58)
Identifying the substrate-induced mechanical and molecular mechanisms that influence chondrocyte behaviour and tissue formation may ultimately lead to the formation of a tissue that more closely resembles natural articular cartilage.
Because of the limitation of our model system, we could not perform a systematic approach to identifying the substrates.
Further observation might help us identify the substrate beneath human culture.
A sulfate molecule adjacent to the Mo identifies the substrate binding pocket.
We provide a new approach to identify the substrate influence on graphene surface.
Untargeted lipidomics analysis using the shotgun method was employed to identify the substrate specificity of L. major PE methyltransferases LmjPEM1 and LmjPEM2 following heterologous expression in yeast lacking their respective, endogenous enzymes [49].
Mass spectrometry data was deconvoluted to identify the substrate cleavage sites and confirmed by Edman sequencing.
However, superposition between human and E. coli SSADH does permit us to identify the substrate binding pocket (Figure 5).
To summarize, we have presented a novel and powerful method that allowed us to quantitatively and qualitatively analyze protease substrate processing in vivo and also rapidly identify the substrate preference of TEVp.
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