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Our approach to cell specific transcriptome profiling of solid tissues involves first identifying the specificity of CD cell-surface markers for cell types within the tissue.
Conflicting results in numerous model systems in identifying the specificity of the antigen during suppression have made it difficult to identify precise parameters and mechanisms of Treg-mediated suppression [15].
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Since autoantibodies are crucial in LN pathogenesis [ 3], identifying the specificities of such nephritogenic antibodies is an important objective.
Furthermore, neither idiotype- nor cancer germline-specific tetramers have identified the specificity of these clones, as such tetramer-positive cells are rarely more than 0.1% of the T-cell population.
Observer programmes on fishing vessels allowed us to identify the specificity of the interaction between common dolphins and fishing gear, and provided low estimates of annual bycaught animals (around 550 animals year−1).
Western blotting was carried out to identify the specificity of antibody.
To date we have identified the specificity of one T-cell clone.
However, more studies are needed to identify the specificity of these two genes in relation to this disease.
To identify the specificity of gene amplification of ACTN4, we previously examined the correlation of gene amplification of a gene near ACTN4.
To identify the specificity of the sdAb-QD probes in vitro, probes sdAb-QDs and sdAb-AF488 were used to stain the fixed cells in a single trial.
Once we fully identified the specificity of the polyclonal antibodies using transiently transfected CHO cells, we tested their utility on xenografts obtained from human breast cancer cell lines.
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